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Platelet-Rich Fibrin (PRF)

CONVENIENTLY LOCATED TO SERVE Newport Beach, Irvine, Huntington Beach, Laguna Beach, Fountain Valley, Aliso Viejo and Laguna Niguel

Close-up of a woman's neck showing visible platysmal bands before treatment.

Platelet-Rich Fibrin (PRF) is a revolutionary treatment that utilizes the body’s natural healing mechanisms to promote skin renewal and repair. Building on the advancements of Platelet-Rich Plasma (PRP), PRF is designed to deliver a slower, sustained release of growth factors, making it an excellent option for delicate areas like the under-eye region.

This minimally invasive procedure offers a natural way to address signs of aging, enhance skin texture, and achieve a more vibrant look. At Metropolis Dermatology in Costa Mesa, we are proud to offer PRF treatments for patients who desire effective and natural rejuvenation solutions.

What is Platelet-Rich Fibrin (PRF)?

Under-eye Platelet-Rich Fibrin (PRF) is an innovative regenerative treatment that uses the body’s growth factors and stem cells to restore the under-eye area. PRF is particularly effective for reducing dark circles, softening fine lines, and improving hollowness beneath the eyes by boosting collagen production and cellular repair. Unlike PRP, which separates only platelets through rapid spinning, PRF is processed more gently, retaining a natural fibrin matrix, white blood cells, and stem cells. This composition supports a gradual, long-lasting release of growth factors, optimizing skin rejuvenation over time.

 

How Does Platelet-Rich Fibrin (PRF) Work?

Blood Collection and PRF Preparation

A small blood sample is drawn from the patient and placed in a centrifuge. The blood is spun at a low speed without anticoagulants, preserving fibrin and stem cells for the PRF layer.

Numbing the Treatment Area

To ensure patient comfort, a topical numbing cream is applied to the under-eye area before the PRF injections.

PRF Injection

Using a fine needle, the PRF is carefully injected into the under-eye area. The fibrin matrix acts as a scaffold, holding growth factors and stem cells in place to ensure a controlled release over time.

Gradual Rejuvenation Process

PRF’s unique formulation releases growth factors over several weeks, stimulating collagen synthesis, tissue repair, and cell growth. This process helps firm and smooth the under-eye area, revealing a more youthful appearance. The entire treatment typically takes less than an hour and involves minimal downtime. Most patients experience mild swelling or bruising, which subsides quickly.

 

Benefits of Platelet-Rich Fibrin (PRF)

  • Prolonged Results
    PRF’s gradual release of growth factors extends the rejuvenation process, providing long-lasting improvements.
  • Ideal for Sensitive Areas
    PRF works exceptionally well on thin, delicate skin, such as the under-eye region, where it reduces dark circles, fine lines, and volume loss.
  • Safe and Natural
    Because PRF is derived from the patient’s own blood and contains no additives, the risk of adverse reactions is extremely low.
  • Boosts Collagen and Elastin
    PRF promotes the production of collagen and elastin, essential components for firm, supple skin.
  • Minimal Downtime
    This minimally invasive treatment allows most patients to resume their daily activities shortly afterward.
Side-by-side comparison of a woman's neck before and after platysmal band injections.

FAQs

How many sessions are needed for optimal results?

For best outcomes, we recommend 2 to 3 sessions spaced about a month apart, followed by maintenance treatments as necessary.

Is the treatment painful?

A numbing cream is applied to ensure comfort, and most patients report minimal discomfort during the procedure.

When will I see results?

Initial improvements can be visible within weeks, with ongoing enhancements as collagen production increases over the following months.

Can PRF be combined with other treatments?

Yes, PRF pairs well with complementary treatments like microneedling or laser therapy for enhanced skin rejuvenation.

Are there any side effects?

Side effects are minimal and may include mild swelling or bruising, which typically resolves within a few days.

Hear from

Real Patients
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Schedule Your Consultation Today!

If you’re looking for a natural and effective way to revitalize your under-eye area or improve overall skin texture, Platelet-Rich Fibrin (PRF) therapy at Metropolis Dermatology in Costa Mesa, CA offers an advanced solution. Contact us today to schedule a consultation and discover how PRF can transform your skin from within!

 

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