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PRF (Dermatology)

CONVENIENTLY LOCATED TO SERVE DTLA, BRENTWOOD, PASADENA, COSTA MESA, AND SAN JOSE.
Close-up of a woman's neck showing visible platysmal bands before treatment.
If you’re seeking a treatment that taps into your body’s own regenerative potential to enhance skin tone, texture, and volume—Platelet-Rich Fibrin (PRF) may be your ideal solution. Unlike synthetic injectables, PRF uses your body’s natural healing cells to stimulate collagen production and support long-term skin rejuvenation.

At Metropolis Dermatology in Brentwood, we offer PRF therapy as part of our advanced regenerative dermatology menu. This biocompatible treatment is designed for those who prefer a holistic approach to anti-aging and skin restoration.

What Is PRF?

PRF is a 100% natural, autologous treatment that uses your own blood to create a powerful blend of platelets, leukocytes (white blood cells), and fibrin. After a simple blood draw, the sample is spun at low speed in a centrifuge to preserve the regenerative cells that help rebuild collagen, repair tissue, and improve overall skin health.

What sets PRF apart from traditional PRP (Platelet-Rich Plasma) is its slower release of growth factors and absence of synthetic additives. This makes PRF a more gentle, sustained option for treating delicate areas such as under the eyes, or for clients with sensitivities to conventional injectables.

 

What Concerns Can PRF Treat?

PRF can be used alone or in combination with other cosmetic treatments to target several key issues:

  • Under-Eye Hollows: Improves volume and thickens the skin to reduce shadowing and crepiness
  • Mid-Face Volume Loss: Restores fullness to cheeks and boosts skin quality
  • Fine Lines & Wrinkles: Softens expression lines with collagen regeneration
  • Scarring & Texture Irregularities: Helps remodel acne scars and improve tone

How Does It Work?

The treatment begins with a standard blood draw, followed by centrifugation to isolate the PRF. Once the plasma is prepared, it’s carefully injected into targeted areas using a fine needle or microcannula. Because it’s drawn from your own body and contains no added chemicals, PRF is well tolerated with minimal risk of allergic reaction or side effects.

 

What to Expect During Your Appointment

A typical PRF session lasts about 45 to 60 minutes and may include the following steps:

  1. Initial consultation and treatment mapping
  2. Blood draw and PRF preparation
  3. Topical numbing for enhanced comfort
  4. Injection into selected areas such as the tear troughs, cheeks, or scalp
  5. Post-care guidance to support healing and collagen remodeling

Downtime is minimal—some mild swelling or bruising may occur but typically resolves within a few days.

 

When Will I See Results?

PRF delivers gradual, natural-looking results that unfold over several weeks. Most patients begin to notice improvements in skin tone, texture, and fullness within 3 to 6 weeks, with optimal results developing after 2 to 3 treatments, spaced about a month apart.

 

How Long Do Results Last?

  • Results typically last 6 to 12 months or more
  • Maintenance sessions every 6 to 12 months can help sustain improvements
  • Combined treatments (like PRF with microneedling or fillers) may enhance longevity

 

Who’s a Good Candidate for PRF?

PRF is suitable for those who:

  • Prefer natural, additive-free solutions
  • Have early signs of aging or volume loss
  • Want to treat delicate areas like the under-eyes
  • Are looking for a chemical-free way to boost collagen and skin vitality
  • Are in good general health with realistic expectations
Side-by-side comparison of a woman's neck before and after platysmal band injections.

FAQs

How is PRF different from PRP?
PRF is spun at a lower speed, preserving more regenerative cells and allowing for a slower, longer-lasting release of growth factors.

Is PRF safe?
Yes. Since it uses your own blood and contains no additives, PRF carries minimal risk of adverse reaction.

Is there any downtime?
Downtime is limited to mild swelling or bruising, which generally subsides in a few days.

Can PRF be combined with other treatments?
Absolutely. PRF enhances the effects of microneedling, fillers, and laser therapies.

Hear from

Real Patients
Metropolis Dermatology-BrandMark-Orange

Schedule Your Consultation Today

PRF offers a regenerative, additive-free option for skin rejuvenation. If you’re looking for a subtle, long-lasting way to enhance your natural beauty, PRF might be the perfect solution. Schedule your personalized consultation at Metropolis Dermatology in Brentwood, LA and explore how this natural treatment can help you restore volume, glow, and confidence—without compromise!

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