Platelet-Rich Fibrin (PRF) is a state-of-the-art regenerative therapy that harnesses your body’s own natural healing abilities to revitalize and restore skin. A step ahead of the earlier Platelet-Rich Plasma (PRP) method, PRF provides a more sustained release of growth factors, offering enhanced results—especially in delicate areas such as under the eyes.
This minimally invasive procedure is an ideal solution for those seeking to minimize signs of aging, improve skin texture, and refresh their appearance using a natural, effective approach. At Metropolis Dermatology in Pasadena, CA, we are proud to offer PRF treatments tailored to patients who desire long-lasting, organic rejuvenation.
What is Platelet-Rich Fibrin (PRF)?
Under-eye PRF is a breakthrough regenerative treatment that utilizes growth factors and stem cells extracted from your own blood to restore and smooth the under-eye area. This technique is especially effective for diminishing dark circles, fine lines, and under-eye hollowness by boosting collagen production and promoting tissue regeneration.
Unlike PRP, which involves high-speed centrifugation that isolates mainly platelets, PRF is prepared at a slower speed. This process preserves valuable components like the fibrin matrix, white blood cells, and stem cells. The result is a natural matrix that releases healing factors gradually over time, supporting extended tissue rejuvenation.
What Can PRF Help Treat?
Platelet-Rich Fibrin is a versatile treatment that targets a variety of concerns, including:
- Uneven Skin Texture & Tone
PRF enhances the overall tone and smoothness of your skin, resulting in a more vibrant, even complexion. - Fine Lines and Wrinkles
By encouraging collagen production, PRF helps soften facial lines and smooth early signs of aging. - Under-Eye Circles
PRF is especially effective at improving dark circles, sagging, and hollowness under the eyes for a refreshed appearance. - Scarring
Whether from acne or injury, PRF can reduce the visibility of scars by promoting tissue regeneration and healing. - Hair Loss
When applied to the scalp, PRF supports hair follicle health, stimulating regrowth and slowing hair thinning in areas affected by pattern hair loss.
How Does Platelet-Rich Fibrin (PRF) Work?
Blood Collection and PRF Separation
A small amount of your blood is drawn and spun in a centrifuge at a low speed. Unlike PRP, no anticoagulants are used, allowing the fibrin matrix and regenerative cells to remain intact and more effective.
Topical Numbing
Before administering PRF, a topical anesthetic is applied to the treatment area to ensure your comfort throughout the process.
PRF Injections
Using a fine needle, the PRF is gently injected into the under-eye region. The fibrin acts as a framework that holds the regenerative components in place, enabling the gradual release of growth factors.
Progressive Rejuvenation
Unlike PRP, which delivers growth factors rapidly, PRF continues to work over several weeks. Collagen production, cellular repair, and tissue tightening occur gradually, leading to smoother, firmer, and more youthful-looking skin.
Topical Application with Complementary Treatments
In addition to targeted injections, PRF can also be applied topically in conjunction with microneedling or laser resurfacing procedures. These combinations enhance absorption and maximize rejuvenation for broader skin concerns such as texture, scarring, and overall tone.
Why Choose Platelet-Rich Fibrin (PRF)?
PRF offers several advantages for patients looking for safe, effective skin rejuvenation:
- Longer-Lasting Improvements. Thanks to its slow release of growth factors, PRF continues working beneath the skin for weeks, supporting extended rejuvenation.
- Gentle on Sensitive Skin. Especially suitable for thin or fragile skin like the under-eye area, PRF helps restore volume, smooth fine lines, and reduce pigmentation naturally.
- Completely Natural and Safe. PRF is derived from your own blood and contains no synthetic additives or anticoagulants, significantly reducing the risk of allergic reactions or complications.
- Stimulates Collagen and Elastin. These essential skin proteins are naturally increased through PRF therapy, improving elasticity, firmness, and skin texture.
- Low Downtime. As a minimally invasive treatment, PRF allows most patients to resume normal activities the same day, with only minor post-treatment symptoms.
FAQs
How long does a PRF treatment take, and is there downtime?
PRF sessions typically take less than an hour to complete. Most patients experience little to no downtime, though mild swelling or bruising may occur around the treated area. These effects usually subside within a few days, allowing you to return to your normal routine quickly.
How many PRF treatments will I need for the best results?
While treatment plans vary based on the individual, most patients benefit from a series of two to three PRF sessions, spaced about four weeks apart. Maintenance treatments can help sustain the results over time.
Is PRF treatment painful?
Discomfort is generally minimal. A numbing cream is used before treatment, and most patients find the PRF injection process well-tolerated.
When can I expect to see results from PRF?
Early improvements may become noticeable within a few weeks, with continued enhancement as collagen rebuilds over several months.
Hear from
Real Patients
Tap Into Nature’s Best Anti-Aging Secret: You
PRF doesn’t just treat the surface—it activates the regenerative force already flowing through you. With no additives, no toxins, and no foreign substances, PRF is one of the most natural ways to restore what time has taken. If you’re ready to give your skin a natural boost from within, Platelet-Rich Fibrin (PRF) at Metropolis Dermatology in Pasadena, CA, is your next step. Book your consultation and discover the glow that was always yours.